Clinical Trials at Duke Comprehensive Cancer Center

If you need additional information about any of the trials listed or would like to inquire about other open trials, please contact Janet Tate Atcock at (919) 681-0680 or Jackie McPherson at (919) 668-1027.

Trial Phase BMT and Cellular Therapies
00012947 I/II A Phase II Study to Evaluate the Efficacy of Epigenetic Modulation in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL)
00000993 I/II Myeloablative Allogeneic Stem Cell Transplantation using a Naive T-cell Depleted Peripheral Blood Stem Cell Graft
00001789 II A Phase II Multicenter Trial of Myeloablative Double Unit Umbilical Cord Blood Transplantation (UCBT) in Adults with Hematologic Malignancy
00001809 II Phase II Safety and Efficacy Study of the Monoclonal Antibody CT-011 in Patients with Diffuse Large B-Cell Lymphoma following Autologous Stem Cell Transplantation
00001982 III A Randomized Double-Blind, Placebo-Controlled Trial of Soluble Tumor Necrosis Factor Receptor: Enbrel (Etanercept) for the Treatment of Acute Non-Infectious Pulmonary Dysfunction (Idiopathic Pneumonic Syndrome) following Allogeneic Cell Transplantation
00005123 Pilot/Feasibility Safety Trial of NK Cell DLIs from 3-5/6 HLA Matched Family Member Following Nonmyeloablative Allogeneic SCT
00009528 II Allogeneic Non-Myeloablative Stem Cell Transplantation Utilizing Mismatched Siblings Stem Cells Purged Using Campath-1H.
N/A Genetic Studies of Bipolar Disorder and Related Traits
00000902 I A Phase I Study of Cancer Peptides Plus GM-CSF and Adjuvant (Montanide ISA 51) Following Completion of Prescribed Chemotherapy or Trastuzumab for TXN2-3M0 or Metastatic Breast Cancer with no Evidence of Disease
00007703 I A Phase I, Open-Label, Dose-Escalation, Multidose Study of CDX-1307, A Mannose Receptor-Targeted hcG-B Vaccine, in Patients with Locally Advanced or Metastatic Breast, Colorectal, Pancreatic, Bladder or Ovarian Cancer
00008771 II Allogeneic Mixed Chimerism Stem Cell Transplantation Utilizing In Vivo & In Vitro Campath-1H for Hemoglobinopathies and Bone Marrow Failure Syndromes.
00008380 II Allogeneic Non-Myeloablative Stem Cell Transplantation Utilizing Matched Family Member Stem Cells Purged Using CAMPATH-1H.
00001360 I A Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following Autologous or Allogeneic Transplantation for AML, CML, ALL, MDS and WT1 Expressing B Cell Malignancies
00009742 II A Phase II Study of Intrathecal Therapy with DepoCYT for Active Lymphomatous or Leukemia Meningitis
Duke Comprehensive Cancer Center Accolades