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Pediatric Blood and Marrow Transplantation
The program provides transplant as a treatment option for a variety of acquired and congenital disorders of children and young adults including hematopoietic malignancies and solid tumors, inherited immune deficiency syndromes, bone marrow failure syndromes, and inherited metabolic diseases. Allogeneic and autologous bone marrow, peripheral stem cell and umbilical cord blood transplants have been performed for pediatric patients to treat these diseases. |
The
Division of Pediatric Blood and Marrow Transplantation
at Duke is an internationally recognized program dedicated to providing
outstanding care and support to pediatric patients who can be helped by
transplantation therapy. The program is known to be a leader in both established techniques and research initiatives. Under the direction of Joanne Kurtzberg, M.D., the program has
performed approximately 1200 autologous and allogeneic transplants in children with
cancer or genetic diseases since 1990. Using a variety of approaches the program has pioneered the use of both matched and
mismatched umbilical cord blood stem cells in patients who do not have a sibling
donor, thus extending this life-saving therapy to many more patients. The cord blood program allows us to identify unrelated
donors quickly (generally within a few weeks). We know that sometimes quick identification can be very
important for patients with inborn errors of metabolism, bone marrow failure, immunodeficiency syndromes,
or advanced leukemias.
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